Afterwards, he lived in London for a short period, working with the famous surgeon Sir Astley Cooper in his dissections of the inguinal region.
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His grandson was the eminent music critic and lexicographer Henry Cope (H. C.) Colles.
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He also described the membranous layer of subcutaneous tissue of the perineum, which came to be known as Colles' fascia.
Abraham Colles (1773-1843) was appointed to the hospital in 1799, where he remained for 42 years.
The quarry was owned by the Colles family, a famous member being Professor Abraham Colles who gave his name to the Colles' fracture.
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