X-Nico

2 unusual facts about B-cell receptor


B-cell receptor

PKCβ phosphorylates (either directly or indirectly) the NF-κB signaling complex protein CARMA1 (the complex itself comprising CARMA1, BCL10, and MALT1).

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These result in recruitment and summoning of the IKK (IkB kinase), TAK1 by several ubiquitylation enzymes also associated with the CARMA1/BCL10/MALT1 complex.



see also