X-Nico

3 unusual facts about Cdc14


Cdc14

The nematode Caenorhabditis elegans makes one Cdc14 (CdCdc14), which localizes to the spindle and centrosomes in mitosis, and to the cytoplasm at interphase.

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A novel role for Cdc14 in eukaryotes was suggested by studies of Phytophthora infestans, a eukaryotic microbe known best as the cause of the Irish Potato Famine.

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Mutants in the ortholog of the fission Schizosaccharomyces pombe exit mitosis normally (unlike S. cerevisiae) but are altered in septation and cytokinesis.


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