He graduated from South Pointe High School in Rock Hill, South Carolina and played college football at the University of South Carolina.
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A native of Rock Hill, South Carolina, Clowney attended South Pointe High School, where he played for the South Pointe Stallions high school football team.
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In the Outback Bowl on January 1, 2013, Clowney helped the Gamecocks to a 33–28 victory over the Michigan Wolverines.