Kid McLaughlin (James Anson McLaughlin, 1888–1934), baseball player for the 1914 Cincinnati Reds
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James Wellington McLaughlin (1840–1903), Ontario doctor and political figure
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James W. McLaughlin (1834–1923), designed the Cincinnati Art Museum and other buildings in Cincinnati
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James C. McLaughlin (1858–1932), politician from the U.S. state of Michigan
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