During the preceding years he had imbibed certain ideas from Lessing's and Herder's writings, which he could not reconcile with the Christian faith.
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During his residence in Rome and the vicinity (1843-74), besides pastoral work and the composition of his principal writings, he was substitute to the secretary of the general of the Jesuits (1843-56), secretary (1856-62), consultor of the Congregation of the Index, and collaborator in the preparation of the Constitution Dei Filius of the First Vatican Council.
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In 1879 some Old Catholics spread the report that Kleutgen had been condemned by the Roman Inquisition to an imprisonment of six years on account of complicity in the poisoning of a Princess von Hohenlohe; but, on 7 March, Juvenal Pelami, Notary of the Inquisition, testified that Kleutgen had never been summoned before the Inquisition upon such a charge, and consequently had not been punished by it.
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