She was consultant at Harvard University's Department of Education (1960-65), Professor of History and Philosophy of Science at Wellesley College (1966-69), Professor of Human Medicine and Philosophy at Michigan State University (1969-78), Senior Research Fellow at the Rockefeller University (1977-82), and Robinson Professor at George Mason University, Fairfax, Virginia.
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After teaching biology at Benenden School, Kent, and Cheltenham Ladies' College, Goodfield lectured in History and Philosophy of Science at Leeds University until 1960.
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While at the Rockefeller University she founded International Health and Biomedicine (UK/USA), a not-for-profit organisation whose objective was to enhance public understanding of science and its impact on global health problems.
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