Colombo succeeded in winning the initial round of the online competition—whose goal was a live performance at the finale of the Last Comic Standing season—but ultimately lost to comedians Theo Von and Josh Wolf.
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To that end, she has been a featured stand-up performer on Rosie O'Donnell's R Family Vacations cruise lines.
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Following her stint on this program, she auditioned for Last Comic Standing in the early summer of 2006.
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She is perhaps best known for her brief but noteworthy audition for the fourth season of NBC's reality series Last Comic Standing, and for her stand-up comedy work in the field of gay rights activism.
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