York Region Transit also operates the 22 King City along Keele, running from Steeles to King Rd in King City.
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While Keele originally ran straight north, today there is a brief cut-off to deviate around the Canadian National and Canadian Pacific Railway corridors, near the former Canada Packers stock yards.
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On August 19, 2005 a freak rainstorm in Toronto caused the Black Creek water level to rise, which caused a section of Finch Avenue West near Sentinel Road (due south of York University between Keele and Jane Streets) to collapse, leaving a deep pit that prevented any pedestrian or vehicular traffic from passing through.