In 1971, at the age of 16, he got his first djing gig, with the help of Robin Lord, and in 1972 he opened The Gallery in SoHo, Manhattan with his older brother Joe Siano.
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On October 18, 2011, Siano reappeared at Studio 54 for the club's "One Night Only" reopening as organized by Sirius XM Radio.
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