At one point, Ralston Purina owned an interest in the St. Louis Blues National Hockey League team; during this period, the arena they then used was referred to as the “Checkerdome”.
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Later, in 1902, he merged with university professor Webster Edgerly, founder of Ralstonism, who was at the time producing breakfast cereals, to form the “Ralston-Purina Company”.
Released in 1983, Tooth Protectors is one of the earliest "advergames" or "promogames" – games with overt tie-ins to retail products – and one of several released that year for the Atari 2600 platform (others included M Network's Kool-Aid Man and Purina's Chase the Chuck Wagon.
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In 1936, they signed a contract to appear regularly on Chicago radio station WLS-AM's National Barn Dance, and were hired in 1937 to perform on Purina Mills' Checkerboard Time radio show, where they sang as The Cackle Sisters.