In 1511, soon after the Portuguese conquest of Malacca, knowing of Siamese ambitions over Malay, Afonso de Albuquerque immediately sent him in a diplomatic mission to the court of the King of Siam Ramathibodi II, traveling in a Chinese junk returning home.
Though unable to conquer Malacca, Siam managed to exact tributes from the Malacca sultanate and other sultanates like Pattani, Pahang, and Kelantan.
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In 1511, however, Malacca fell to the Portuguese under Afonso de Albuquerque.